3 reasons Harvard & Stanford scientists think Saffron is the key to a happy you

Saffron isn’t just the world’s most precious spice - it’s now seen as a go-to for those of us wanting to feel more positive about life.

Saffron has been shown to impact several of the core biological mechanisms that affect our mood. And that’s why our Harvard and Stanford scientists have made Saffron the cornerstone of our Karmacist Mood FormulationStudies have revealed:

1. Saffron boosts ‘happy hormones’

Saffron impacts two hormones that are critical to our moods: serotonin and dopamineIndeed, serotonin and dopamine are known as ‘happy chemicals’. Serotonin is a mood stabiliser, whilst dopamine is a ‘reward’ chemical that plays an important role in motivating behaviour. 

Saffron appears to operate at a deep, deep level - by impacting the fundamental process of gene expression. The spice’s extract reduces the expression of the serotonin transporter gene (SERT or 5-HTT) which is involved in recycling serotonin, and increases the expression of dopamine in the brain.


2. Saffron modulates anti-inflammatory molecules in the brain

Inflammation ((the actions of the immune system) in the brain has been linked to depression. Saffron is rich in Crocetin and Crocin, molecules which have potent antioxidant properties, to help modulate systemic inflammation.


3. Saffron helps control cortisol 

Cortisol - the ‘alarm system’ hormone which circulates in your blood after a stressful event - can also be regulated by Saffron. Here’s how: the Crocin in Saffron has been shown to reduce the gene expression of glucocorticoid receptors - which recognise stress hormones such as cortisol and activate an anxiety response in the brain.

By harnessing the power of this rare botanical - as uncovered by Nutrigenomics, nutritional psychiatry and epigenetics studies - Karmacist scientists have developed the Mood Formulation, which delivers a precise combination of clinically-proven Saffron, blended with resilience-building Passionflower, and key micronutrients that support normal psychological function* and help promote emotional balance. 

Read more on Saffron in Dr Vittorio Sebastiano's Deep Science article here.

*Folic Acid and Vitamin B12 contribute to normal psychological function



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